On average, listings lease in the $10's per square foot per year. The Downtown Mesa region is experiencing a a rise in rates. In the last 3 months, the median rate rose $3 per sqft per year. That's a 21% rise in rent.
Compared to the rest of the Phoenix Metropolitan Area market, the Downtown Mesa region has lower rates, so you should have no trouble finding a great deal in this depreciated region.
In the last 90 days, 13 listings have come on the market, which means listings most likley are going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,000 sqft. Most buildings in this area are close to 2 floors. Most buildings in this area were built in 1960 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Public administration is the dominant industry in this area. Commute by car is the most popular way to get to work amongst Downtown Mesa folk. Commuting close to 20 minutes a day is the norm for those who opt to reside in this part of town.